Rosalind [hnn] is a really neat sequence of bioinformatics problems and a grader (it generates a data file and checks your output - you program it however you like, but you've got five minutes from getting the data to submit your response).
It's got a forum system, badges, the whole nine yards, and a branding thing if you want to use it in your class.
I'm working through the sequence - but it's a good target application, too. But yeah, bioinformatics is kind of neat!
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